Efficacy and Safety of Fecal Microbiota Transplantation for Irritable Bowel Syndrome

Who is this study for? Patients with Irritable Bowel Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. FMT has a higher cure rate than standard antibiotic treatment for recurrent Clostridium difficile infections,and shows promising results in Inflammatory bowel disease(IBD).However, few studies have evaluated whether FMT is effective to treat Irritable bowel syndrome(IBS).The investigators propose to determine the efficiency and safety of FMT in patients with Irritable bowel syndrome.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

⁃ To be considered eligible for enrolment into the study, subjects must:

• Be able to give written informed consent.

• Males and females aged \>18 and \<75

• Have IBS as defined by the Rome IV criteria

Locations
Other Locations
China
Guangzhou First People's Hospital
RECRUITING
Guangzhou
Contact Information
Primary
Hongli Huang, MM
honglisums@126.com
86-13631316718
Backup
Huiting Chen, MM
gracy1977@tom.com
86-13926055294
Time Frame
Start Date: 2018-08-10
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 120
Treatments
Experimental: fecal microbiota transplantation
fecal microbiota transplantation
Sham_comparator: placebo fecal microbiota transplantation
Infusion of sham
Sham_comparator: Traditional treatments
Traditional treatments according to associated guidelines such as probiotics, antibiotics or antidepressants
Related Therapeutic Areas
Sponsors
Leads: Guangzhou First People's Hospital

This content was sourced from clinicaltrials.gov